Analysis of centrally acting muscle relaxants marketed in Brazil from the perspective of Elderly Care

Authors

  • Nelson Machado do Carmo Júnior Hospital Risoleta Tolentino Neves. Universidade Federal de Minas Gerais
  • Adriano Max Moreira Reis Universidade Federal de Minas Gerais

DOI:

https://doi.org/10.22421/15177130-2017v18n1p108

Keywords:

Muscle Relaxants, Centrally acting, Elderly Health. Medicine Package Inserts, Product Surveillance, Postmarketing.

Abstract

Objective: To analyze the scientific evidence regarding the therapeutic use and safety of muscle relaxant medicines registered in Brazil from the perspective of the health of the elderly.
Methods: This is a study of the analysis of the supply of medicines containing group M03B drugs – Centrally acting muscle relaxants of the Anatomical Therapeutic Chemical classification. The M03B group drugs registered in Brazil were observed. The scientific evidence on safety and efficacy has been investigated. The availability of safety information in the package leaflet was analyzed.
Results: We identified 18 drugs from group M03B, of which 7 (38.9%) are registered in Brazil. Of the 67 specialties registered, 35 (52.2%) are pharmacological associations.
Conclusion: Evidence for the use of musclerelaxants in the elderly is limited. The package leaflets do not contain relevant information on adverse events.

Author Biographies

Nelson Machado do Carmo Júnior, Hospital Risoleta Tolentino Neves. Universidade Federal de Minas Gerais

Pharmaceutical. Specialist in Health of the Elderly by Hospital Risoleta Tolentino Neves / UFMG. Specialist in Public Health, Faculdade Anhanguera (SP).

Adriano Max Moreira Reis, Universidade Federal de Minas Gerais

PhD in Sciences by the Fundamental Nursing Program of the University of São Paulo, Campus Ribeirão Preto (2009). Master in Pharmaceutical Sciences, Federal University of Minas Gerais (1998). He is currently an Adjunct Professor at the Faculty of Pharmacy of the Federal University of Minas Gerais.

Published

2017-07-17

How to Cite

1.
Carmo Júnior NM do, Reis AMM. Analysis of centrally acting muscle relaxants marketed in Brazil from the perspective of Elderly Care. Espac. Saude [Internet]. 2017 Jul. 17 [cited 2024 Dec. 4];18(1):108-16. Available from: https://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/351

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